Glossary of Abbreviations:BD (Barlow’s Disease), CAI (coaptation area index), ED (end diastole), FE (finite element), LS (late systole), MAA (mitral annular area), MAD (mitral annular disjunction), MR (mitral regurgitation), MRS (mitral regurgitation start), MVO (mitral valve opening), SAM (systolic anterior motion), SLA (segmented leaflet area)
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Funding Statement: This document is the result of the research project funded by the Trond Mohn Foundation (TMS2019TMT09).
Informed Consent Statement: The Institutional Review Board (IRB) or equivalent ethics committee of Haukeland University Hospital approved the study protocol and publication of data. The patient(s) provided informed written consent for the publication of the study data.Date of approval 28/11/2018. Approval number: 2016/1132-8
Central Picture: Simulations of moderate annular reductions versus conventional annuloplasty rings
In silico analysis by 3D echocardiography have shown that moderate annuloplasty ring scaling secures the same leaflet coaptation area in the individual patient compared with post-operative findings.
In silico analysis in Barlow’s patients demonstrates that annuloplasty with only moderate annular reduction may be sufficient to achieve optimal coaptation as compared to conventional annuloplasty procedures. This novel method may prove helpful in pre-operative planning and selection of the ideal annuloplasty ring size.
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