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Adult: Coronary: Letters to the Editor| Volume 13, P199, March 2023

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Reply: The right internal mammary artery graft is a mirage

Open AccessPublished:November 25, 2022DOI:https://doi.org/10.1016/j.xjon.2022.11.008
      Reply to the Editor:
      The author reported no conflicts of interest.
      The Journal policy requires editors and reviewers to disclose conflicts of interest and to decline handling or reviewing manuscripts for which they may have a conflict of interest. The editors and reviewers of this article have no conflicts of interest.
      First, we should not put total arterial and multiple arterial grafts in the same sentence and compare them with single arterial grafts but rather look at each graft individually. The conclusion of our manuscript
      • Alboom M.
      • Browne A.
      • Sheth T.
      • Zheng Z.
      • Dagenais F.
      • Noiseux N.
      • et al.
      Conduit selection and early graft failure in coronary artery bypass surgery: a post hoc analysis of the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) coronary artery bypass grafting study.
      is that the left internal mammary artery and radial artery performed as expected, whereas vein grafts performed better than expected. However, high rates of right internal mammary artery (RIMA) failure are worrisome and highlight the need for a thorough evaluation of the patency and safety of the RIMA in coronary artery bypass grafting surgery.
      The RIMA graft has a greater rate of failure due to the harvesting by the skeletonization technique, and this has been demonstrated in Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS)
      • Lamy A.
      • Eikelboom J.
      • Sheth T.
      • Connolly S.
      • Bosch J.
      • Fox K.A.
      • et al.
      Rivaroxaban, aspirin, or both to prevent early coronary bypass graft occlusion: the COMPASS CABG study.
      ,
      • Lamy A.
      • Browne A.
      • Sheth T.
      • Zheng Z.
      • Dagenais F.
      • Noiseux N.
      • et al.
      Skeletonized vs pedicled internal mammary artery graft harvesting in coronary artery bypass surgery: a post hoc analysis from the COMPASS trial.
      and Arterial Revascularization Trial (ART).
      • Gaudino M.
      • Audisio K.
      • Rahouma M.
      • Chadow D.
      • Cancelli G.
      • Soletti G.J.
      • et al.
      ART Investigators
      Comparison of long-term clinical outcomes of skeletonized vs pedicled internal thoracic artery harvesting techniques in the Arterial Revascularization Trial.
      Case closed. The in situ configuration (going behind the heart to the circumflex artery), in comparison with a Y graft coming from the left internal mammary artery, is associated with a lower patency in our manuscript but also with worse clinical outcomes in the reference provided by Prof Formica and his colleagues. They are correct saying this is a surgeon-related factor rather than a biological one. It is a technical problem, and we must fix it.
      The recent network analysis by Gaudino and colleagues
      • Gaudino M.
      • Audisio K.
      • Di Franco A.
      • Alexander J.H.
      • Kurlansky P.
      • Boening A.
      • et al.
      Radial artery versus saphenous vein versus right internal thoracic artery for coronary artery bypass grafting.
      is compelling evidence that the right internal thoracic artery is not better than a vein and inferior to a radial artery. We must also keep in mind that vein grafts are better in recent trials than older trials, likely due to the use of cholesterol-reducing medication.
      While radial arteries have been tested in good trials, the best right internal thoracic artery configuration has not been demonstrated. There is an urgent need for a thorough evaluation of the patency and safety of the RIMA in coronary artery bypass grafting surgery, and surgeons should know their results and present them. It is an issue of intellectual integrity and patient safety.

      References

        • Alboom M.
        • Browne A.
        • Sheth T.
        • Zheng Z.
        • Dagenais F.
        • Noiseux N.
        • et al.
        Conduit selection and early graft failure in coronary artery bypass surgery: a post hoc analysis of the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) coronary artery bypass grafting study.
        J Thorac Cardiovasc Surg. June 2, 2022; ([Epub ahead of print])
        • Lamy A.
        • Eikelboom J.
        • Sheth T.
        • Connolly S.
        • Bosch J.
        • Fox K.A.
        • et al.
        Rivaroxaban, aspirin, or both to prevent early coronary bypass graft occlusion: the COMPASS CABG study.
        J Am Coll Cardiol. 2019; 73: 121-130
        • Lamy A.
        • Browne A.
        • Sheth T.
        • Zheng Z.
        • Dagenais F.
        • Noiseux N.
        • et al.
        Skeletonized vs pedicled internal mammary artery graft harvesting in coronary artery bypass surgery: a post hoc analysis from the COMPASS trial.
        JAMA Cardiol. 2021; 6: 1042-1049
        • Gaudino M.
        • Audisio K.
        • Rahouma M.
        • Chadow D.
        • Cancelli G.
        • Soletti G.J.
        • et al.
        • ART Investigators
        Comparison of long-term clinical outcomes of skeletonized vs pedicled internal thoracic artery harvesting techniques in the Arterial Revascularization Trial.
        JAMA Cardiol. 2021; 6: 1380-1386
        • Gaudino M.
        • Audisio K.
        • Di Franco A.
        • Alexander J.H.
        • Kurlansky P.
        • Boening A.
        • et al.
        Radial artery versus saphenous vein versus right internal thoracic artery for coronary artery bypass grafting.
        Eur J Cardio Thorac Surg. 2022; 62: ezac345https://doi.org/10.1093/ejcts/ezac345

      Linked Article

      • Multiple and total arterial grafts are not a mirage anymore!
        JTCVS OpenVol. 13
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          The use of single arterial graft (SAG) is the most used technique for coronary artery bypass grafting (CABG), although a body of literature reports an increasing use of multiple (MAG) and total arterial graft (TAG).1,2 Unfortunately, the use of MAG/TAG is still underused, being reported between 10% and 35% in Europe and North America.3 Factors such as higher consuming time, greater prone to spasm, and technical harvesting lead surgeons to prefer SAG to MAG/TAG (Figure 1). In addition, the latest guidelines encourage percutaneous coronary intervention in 3-vessel coronary artery disease patients with limited coronary calcification and favor the use of CABG in patients with extensive coronary calcifications.
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